Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134309 | 0.79 | CHRM2 (0.38) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL18343819 | 0.78 | LMNA (0.41) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11806002 | 0.78 | LMNA (0.41) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11679220 | 0.77 | TSHR (0.39) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9016141 | 0.77 | TSHR (0.39) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL3973873 | 0.76 | LMNA (0.45) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL16417086 | 0.76 | LMNA (0.39) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL8431987 | 0.74 | ALDH1A1 (0.39) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL28501705 | 0.73 | LMNA (0.37) | CHRM1CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL11805305 | 0.73 | DNM1 (0.41) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534766-B2 | PROCESS FOR PREPARING POLYURETHANE FOAM | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-01-17 | — | — | EP | claimed |
| EP-1534766-B1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GEN ELECTRIC (US) | 2009-02-18 | — | — | EP | claimed |
| EP-1332167-B1 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | GEN ELECTRIC (US) | 2008-09-17 | — | — | EP | claimed |
| EP-1534766-A1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GENERAL ELECTRIC COMPANY (US) | 2005-06-01 | — | — | EP | claimed |
| US-6818675-B2 | USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST | GENERAL ELECTRIC COMPANY | 2004-11-16 | — | — | US | claimed |
| WO-2004013201-A1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GENERAL ELECTRIC COMPANY (US) | 2004-02-12 | — | — | WO | claimed |
| US-20040029986-A1 | Process for preparing polyurethane foam | CROMPTON CORPORATION | 2004-02-12 | — | — | US | claimed |
| EP-1332167-A2 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | Crompton Corporation (US) | 2003-08-06 | — | — | EP | claimed |
| US-6423756-B1 | USING CATALYST SYSTEM | CROMPTON CORPORATION | 2002-07-23 | — | — | US | claimed |
| WO-2002048229-A2 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | CROMPTON CORPORATION (US) | 2002-06-20 | — | — | WO | claimed |
| EP-1534766-B2 | PROCESS FOR PREPARING POLYURETHANE FOAM | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-01-17 | — | — | EP | disclosed |
| CN-1478111-B | Method for improving polyurethane foam performance | GEN ELECTRIC | 2012-10-17 | — | — | CN | disclosed |
| CN-100509901-C | Process to improve polyurethane foam performance | GEN ELECTRIC (US) | 2009-07-08 | — | — | CN | disclosed |
| EP-1534766-B1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GEN ELECTRIC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1332167-B1 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | GEN ELECTRIC (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2002048229-A3 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | CROMPTON CORP (US) | 2002-12-27 | — | — | WO | disclosed |
| US-6423756-B1 | USING CATALYST SYSTEM | CROMPTON CORPORATION | 2002-07-23 | — | — | US | disclosed |
| US-6423756-B1 | USING CATALYST SYSTEM | CROMPTON CORPORATION | 2002-07-23 | — | — | US | disclosed |
| WO-2002048229-A2 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | CROMPTON CORPORATION (US) | 2002-06-20 | — | — | WO | disclosed |
| WO-2002048229-A2 | PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE | CROMPTON CORPORATION (US) | 2002-06-20 | — | — | WO | disclosed |