Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 1.00 |
| ▸ | PDK2 | Q15119 | 2/20 | 1.00 |
| ▸ | PDK3 | Q15120 | 2/20 | 1.00 |
| ▸ | PDK4 | Q16654 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 3/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.83 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.83 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.83 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.83 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 1/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9111475 | 1.00 | PDK1 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| SCHEMBL5134413 | 1.00 | PDK1 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL5711211 | 0.91 | PDK1 (0.83) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL678976 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL9892651 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL10038576 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL19798150 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL14700492 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL28888 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 | |
| Abietic Acid SCHEMBL16268652 | 0.91 | HSD17B10 (1.00) | PDK1PDK2PDK3PDK4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648706-A2 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES | The Penn State Research Foundation (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078667-A2 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-14 | — | — | WO | claimed |
| US-7427324-B1 | Methods of making quinacridone nanoscale pigment particles | XEROX CORPORATION (US) | 2008-09-23 | — | — | US | claimed |
| US-20020058734-A1 | Useful for incorporating polymers using low shear mixing techniques | J.S.G. ENTERPRISES, INC. | 2002-05-16 | — | — | US | disclosed |