Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586329 | 0.94 | P2RY12 (0.54) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL4871507 | 0.93 | P2RY12 (0.55) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL5014112 | 0.87 | P2RY12 (0.63) | P2RY12KDM4ECYP3A4CYP2C9 | |
| SCHEMBL3221673 | 0.86 | P2RY12 (0.69) | P2RY12KDM4ECYP3A4CYP2C9 | |
| SCHEMBL3585012 | 0.85 | P2RY12 (0.55) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3584927 | 0.85 | P2RY12 (0.51) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL4740960 | 0.85 | P2RY12 (0.57) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3585342 | 0.84 | P2RY12 (0.56) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL3586010 | 0.84 | ALDH1A1 (0.71) | P2RY12ALDH1A1KDM4EACACB | |
| SCHEMBL3327054 | 0.84 | P2RY12 (0.56) | P2RY12ALDH1A1KDM4EL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904474-A1 | NEW PYRIDINE ANALOGUES | AstraZeneca AB (SE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007008140-A1 | NEW PYRIDINE ANALOGUES | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |