Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070387 | 0.80 | MAPT (0.42) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL12006510 | 0.78 | — | — | |
| SCHEMBL1683063 | 0.78 | ALDH1A1 (0.45) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL7399794 | 0.77 | MAPT (0.39) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL18756273 | 0.77 | CHRM2 (0.37) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL5865605 | 0.77 | CYP3A4 (0.38) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL17865874 | 0.77 | CYP3A4 (0.38) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| SCHEMBL16215738 | 0.77 | — | — | |
| SCHEMBL28273368 | 0.76 | TSHR (0.49) | MAPTCACNA1BAPBA1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL18725638 | 0.76 | CHRM2 (0.36) | MAPTCACNA1BAPBA1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060019936-A1 | Methods and compositions for treating cancer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-01-26 | — | — | US | claimed |
| US-9289511-B2 | Bioconjugated nanoparticles | THE BOEING COMPANY (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140207126-A1 | BIOCONJUGATED NANOPARTICLES | THE BOEING COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-20080317768-A1 | BIOCONJUGATED NANOPARTICLES | BOEING COMPANY (US) | 2008-12-25 | — | — | US | disclosed |
| WO-2008156460-A1 | BIOCONJUGATED NANOPARTICLES | THE BOEING COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-1773754-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER | Massachussets Institute of Technology (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20060019936-A1 | Methods and compositions for treating cancer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005086974-A2 | METHODS AND COMPOSITIONS FOR TREATING CANCER | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-09-22 | — | — | WO | disclosed |