Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751596 | 0.94 | SPHK2 (0.41) | GPR84FFAR1SPHK2SPHK1CETP | |
| SCHEMBL8106178 | 0.92 | SPHK2 (0.44) | GPR84FFAR1SPHK2SPHK1CETP | |
| SCHEMBL6266665 | 0.80 | GPR84 (0.57) | GPR84FFAR1MAPT | |
| SCHEMBL6268236 | 0.80 | GPR84 (0.57) | GPR84FFAR1MAPT | |
| SCHEMBL5486823 | 0.78 | — | — | |
| SCHEMBL6050258 | 0.76 | TSHR (0.40) | TSHR | |
| SCHEMBL28838512 | 0.73 | MAPT (0.48) | SPHK2SPHK1CETPTP53CYP1A2 | |
| SCHEMBL27806454 | 0.71 | MEN1 (0.45) | SPHK2SPHK1CETPTP53CYP1A2 | |
| SCHEMBL30269756 | 0.69 | — | — | |
| SCHEMBL3021028 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080254508-A1 | TYPE I POLYKETIDE SYNTHASE EXTENDER UNITS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-10-16 | — | — | US | claimed |
| US-8759031-B2 | Type I polyketide synthase extender units | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-06-24 | — | — | US | disclosed |
| US-20080254508-A1 | TYPE I POLYKETIDE SYNTHASE EXTENDER UNITS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-10-16 | — | — | US | disclosed |