SCHEMBL5135074

SCHEMBL5135074

[c]1ccccc1C1(c2ccccc2)CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.38
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HSD11B1 P28845 2/20 0.38
HSD11B2 P80365 2/20 0.38
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
CYP2B6 P20813 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
PRCP P42785 1/20 0.38
SLC6A3 Q01959 1/20 0.38
GRIN1 Q05586 1/20 0.38
KCNH2 Q12809 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379632 0.88 ESR1 (0.34) ALDH1A1L3MBTL1ESR1ESR2GRIN2D
SCHEMBL6567713 0.83 PGR (0.34) ALDH1A1L3MBTL1ESR1ESR2SLC6A2
SCHEMBL54982 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL30078304 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL30877902 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL24157288 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL30877914 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL28378542 0.77 ESR1 (0.58) OPRM1ALDH1A1L3MBTL1ESR1ESR2
Ammonia Solution, Strong SCHEMBL7989528 0.75 ESR1 (0.56) OPRM1ALDH1A1L3MBTL1ESR1ESR2
SCHEMBL1515174 0.75 ESR1 (0.56) OPRM1ALDH1A1L3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171143-A1 Process For Preparation Of Optical Compensatory Sheet FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
WO-2006064950-A1 PREPARATION OF AN OPTICAL COMPENSATION SHEET USING PHOTOSENSITIVE COMPOUNDS FUJIFILM CORPORATION (JP) 2006-06-22 WO disclosed