Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135532 | 1.00 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL20788032 | 0.92 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2PKMAKR1C3 | |
| SCHEMBL20788033 | 0.92 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2PKMAKR1C3 | |
| SCHEMBL3616763 | 0.89 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL3616760 | 0.89 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL14508502 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2PKMNPSR1 | |
| SCHEMBL20788020 | 0.85 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2PKMAKR1C3 | |
| SCHEMBL20788019 | 0.85 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2PKMAKR1C3 | |
| SCHEMBL27455901 | 0.82 | AKR1C3 (0.64) | KDM4EALDH1A1SMN1; SMN2PKMAKR1C3 | |
| SCHEMBL3169519 | 0.81 | KMT2A (0.65) | KDM4EPKMAKR1C3AKR1C2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | claimed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | claimed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | claimed |
| EP-1948203-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20070106035-A1 | Aromatic di-acid-containing poly (ester amide) polymers and methods of use | MEDIVAS, LLC (US) | 2007-05-10 | — | — | US | disclosed |
| WO-2007050583-A2 | AROMATIC DI-ACID-CONTAINING POLY (ESTER AMIDE) POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2007-05-03 | — | — | WO | disclosed |