Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL5136310

C=C(C)C(=O)O.COC.OCCOCCO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
MAPK1 P28482 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.39
THRB P10828 2/20 0.36
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
TGFBR1 P36897 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL9297935 0.98 MEN1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL4014249 0.98 MEN1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Methacrylic Acid SCHEMBL2905298 0.98 MEN1 (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL33375 0.95 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL24262 0.95 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL5169334 0.95 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL10495579 0.95 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9839735 0.95 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL9314003 0.93 MEN1 (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL8661497 0.93 MEN1 (0.52) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113103697-B Fluorine-silicon hydrogel colored contact lens and preparation process thereof 苏州瑞尔康科技有限公司 2022-08-09 CN claimed
CN-112812243-B Composition for preparing oxygen-permeable fluorosilicone hydrogel contact lens, oxygen-permeable fluorosilicone hydrogel contact lens and preparation method 苏州瑞尔康科技有限公司 2021-08-03 CN claimed
CN-113103697-A Fluorosilicone hydrogel colored contact lens and preparation process thereof 苏州瑞尔康科技有限公司 2021-07-13 CN claimed
CN-112812243-A Oxygen-permeable fluorosilicone hydrogel contact lens and preparation method thereof 苏州瑞尔康科技有限公司 2021-05-18 CN claimed
CN-113103697-B Fluorine-silicon hydrogel colored contact lens and preparation process thereof 苏州瑞尔康科技有限公司 2022-08-09 CN disclosed
CN-112812243-B Composition for preparing oxygen-permeable fluorosilicone hydrogel contact lens, oxygen-permeable fluorosilicone hydrogel contact lens and preparation method 苏州瑞尔康科技有限公司 2021-08-03 CN disclosed
CN-113103697-A Fluorosilicone hydrogel colored contact lens and preparation process thereof 苏州瑞尔康科技有限公司 2021-07-13 CN disclosed
CN-112812243-A Oxygen-permeable fluorosilicone hydrogel contact lens and preparation method thereof 苏州瑞尔康科技有限公司 2021-05-18 CN disclosed
US-8466232-B2 Biodegradable grafted copolymers FIRMENICH SA (CH) 2013-06-18 US disclosed
EP-1753806-B1 BIODEGRADABLE GRAFTED COPOLYMERS FIRMENICH & CIE (CH) 2008-07-30 EP disclosed
US-20070054816-A1 BIODEGRADABLE GRAFTED COPOLYMERS FIRMENICH SA (CH) 2007-03-08 US disclosed
EP-1753806-A1 BIODEGRADABLE GRAFTED COPOLYMERS FIRMENICH SA (CH) 2007-02-21 EP disclosed
WO-2005108471-A1 BIODEGRADABLE GRAFTED COPOLYMERS FIRMENICH SA (CH) 2005-11-17 WO disclosed