Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL5169334 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL10495579 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL24262 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL33375 | 1.00 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Tetraethylene Glycol SCHEMBL33688 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Methacrylic Acid SCHEMBL478108 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Hexaethylene Glycol SCHEMBL2347830 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Methacrylic Acid SCHEMBL10529387 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Pentaethylene Glycol SCHEMBL672104 | 0.98 | MEN1 (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL8659237 | 0.98 | TSHR (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003310-A1 | PROCESS FOR SURFACE-GRAFTING OF FORMED MATERIALS, IN PARTICULAR ALSO MICROPOROUS MEMBRANES MADE FROM NITROGEN CONTAINING POLYMERS | SARTORIUS AG (DE) | 1991-03-21 | — | — | WO | disclosed |