Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147243 | 0.90 | HTR6 (0.80) | HTR6 | |
| SCHEMBL3143100 | 0.83 | HTR6 (0.87) | HTR6 | |
| SCHEMBL13809320 | 0.82 | HTR6 (0.70) | HTR6 | |
| SCHEMBL3152523 | 0.82 | HTR6 (0.80) | HTR6 | |
| SCHEMBL3154616 | 0.81 | HTR6 (0.83) | HTR6 | |
| SCHEMBL3157096 | 0.80 | HTR6 (0.52) | HTR6 | |
| SCHEMBL3148939 | 0.80 | HTR6 (0.52) | HTR6 | |
| SCHEMBL3261218 | 0.79 | HTR6 (0.79) | HTR6 | |
| SCHEMBL4151353 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3152386 | 0.79 | HTR6 (0.51) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648468-B1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY | ESTEVE LABOR DR (ES) | 2008-09-24 | — | — | EP | disclosed |