Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL870484 | 0.82 | CTSD (0.62) | CTSDSTAT3HTTNPC1RAB9A | |
| SCHEMBL29658169 | 0.82 | CTSD (0.62) | CTSDSTAT3LMNAHTTNPC1 | |
| SCHEMBL322168 | 0.82 | CTSD (0.62) | CTSDSTAT3LMNAHTTNPC1 | |
| SCHEMBL2098153 | 0.82 | KMT2A (0.55) | LMNAHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26118521 | 0.81 | CTSD (0.56) | CTSDSTAT3HTTNPC1RAB9A | |
| Formaldehyde SCHEMBL28303539 | 0.81 | SMN1; SMN2 (0.64) | CTSDSTAT3LMNAHTTNPC1 | |
| SCHEMBL29365231 | 0.80 | HTT (0.78) | CTSDSTAT3LMNAHTTNPC1 | |
| SCHEMBL29432808 | 0.80 | SMN1; SMN2 (0.68) | CTSDSTAT3LMNAHTTNPC1 | |
| SCHEMBL49886 | 0.80 | CTSD (0.60) | CTSDSTAT3HTTNPC1RAB9A | |
| SCHEMBL54071 | 0.80 | SMN1; SMN2 (0.68) | CTSDSTAT3LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299401-A | A kind of 3- benzyls substituted cumarin-imidazole salt compound and preparation method thereof | 红河学院 | 2018-07-20 | — | — | CN | claimed |
| CN-101384594-A | Condensed heterocyclic compounds useful as dpp-iv inhibitors | NOVARTIS AG (CH) | 2009-03-11 | — | — | CN | claimed |
| US-20080119522-A1 | 5,6-dichloro-2-(2,2,2-trifluoro-ethyl)-1H-benzimidazole for example; use for prostate cancer, benign prostatic hyperplasia (BPH), hirsutism, alopecia, anorexia nervosa, breast cancer, acne, AIDS, cachexia, as a male contraceptive, and/or as a male performance enhancer | NG RAYMOND | 2008-05-22 | — | — | US | claimed |
| EP-1812406-A2 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-01 | — | — | EP | claimed |
| US-20060111402-A1 | Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-25 | — | — | US | claimed |
| WO-2006039215-A2 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-13 | — | — | WO | claimed |
| US-6096836-A | OXYGEN CONTAINING AROMATIC CATALYST AND ALUMINUM COMPOUND | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-08-01 | — | — | US | claimed |
| US-5482816-A | RESISTS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-01-09 | — | — | US | claimed |
| US-5376498-A | Blend of an alkali-soluble resin, compound that generates an acid upon irradiation, functional aromatic compound and a phenolic compound | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| EP-0542572-A1 | Negative type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| US-4361514-A | Carbon analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1982-11-30 | — | — | US | claimed |
| US-4282149-A | Carbon and oxygen analogs of penicillin | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1981-08-04 | — | — | US | claimed |
| US-4143046-A | CARBON AND OXYGEN ANALOGS OF PENICILLIN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1979-03-06 | — | — | US | claimed |
| US-4075340-A | ANTIINFLAMMATORY, ANTIARRYTHMIC, ANTICOAGULANTS | PARCOR (FR) | 1978-02-21 | — | — | US | claimed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-11764043-B2 | Methods of mass spectrometry quantitation using cleavable isobaric tags and neutral loss fragmentation | THERMO FINNIGAN LLC | 2023-09-19 | — | — | US | disclosed |
| US-20230212132-A1 | AMINIMIDE COMPOUND, AMINIMIDE COMPOSITION, CURING AGENT, EPOXY RESIN COMPOSITION, METHOD FOR PRODUCING AMINIMIDE COMPOUND, ENCAPSULANT, AND ADHESIVE | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-07-06 | — | — | US | disclosed |
| US-4125533-A | STABILIZERS | SANKYO CO. LTD. (JP) | 1978-11-14 | — | — | US | disclosed |
| US-4016168-A | STABILIZERS FOR POLYMERS | SANKYO COMPANY LIMITED (JA) | 1977-04-05 | — | — | US | disclosed |
| US-3971825-A | (5,6) (10,11) BIS-METHYLENE, BRONCHODILATORS | SANKYO COMPANY LIMITED (JA) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111402-A1 | Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) | AR, NR5A1, ESRRA | CTSD 3149/4885STAT3 523/4885LMNA 3422/4885 |
| US-20230212132-A1 | AMINIMIDE COMPOUND, AMINIMIDE COMPOSITION, CURING AGENT, EPOXY RESIN COMPOSITION, METHOD FOR PRODUCING AMINIMIDE COMPOUND, ENCAPSULANT, AND ADHESIVE | ITGAL, VCL, RPL39 | CTSD 4359/4885STAT3 4587/4885LMNA 1690/4885 |
| US-20080119522-A1 | 5,6-dichloro-2-(2,2,2-trifluoro-ethyl)-1H-benzimidazole for example; use for prostate cancer, benign prostatic hyperplasia (BPH), hirsutism, alopecia, anorexia nervosa, breast cancer, acne, AIDS, cachexia, as a male contraceptive, and/or as a male performance enhancer | AR, FSHR, BRDT | CTSD 1323/4885STAT3 414/4885LMNA 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.