Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561797 | 0.91 | TP53 (0.67) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30432383 | 0.82 | HTT (0.58) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL560804 | 0.81 | TP53 (0.48) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL21375730 | 0.80 | ALDH1A1 (0.58) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL3019223 | 0.79 | ALDH1A1 (0.61) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL663520 | 0.78 | MAPT (0.50) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL2374740 | 0.78 | MAPT (0.50) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL663519 | 0.78 | MAPT (0.50) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL19123323 | 0.77 | ALDH1A1 (0.59) | HTTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL26115468 | 0.77 | MAPT (0.51) | ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951652-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | Astra Zeneca AB (SE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057643-A1 | PROCESS FOR PREPARING BETA- (FLUOROPHENYL) -PROPANOATE ESTER DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-24 | — | — | WO | disclosed |