Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1897332 | 0.82 | SIGMAR1 (0.98) | SIGMAR1KCNH2 | |
| SCHEMBL467323 | 0.81 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL467171 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL466940 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL467027 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL4560092 | 0.80 | SIGMAR1 (0.78) | SIGMAR1KCNH2 | |
| SCHEMBL467246 | 0.80 | SIGMAR1 (1.00) | SIGMAR1KCNH2 | |
| SCHEMBL467159 | 0.80 | SIGMAR1 (0.77) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL1900361 | 0.80 | SIGMAR1 (0.80) | SIGMAR1KCNH2 | |
| SCHEMBL19988158 | 0.79 | SIGMAR1 (0.85) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994032-A1 | PYRAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS | Laboratorios del Dr. Esteve S.A. (ES) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007098953-A1 | PYRAZOLE DERIVATIVES AS SIGMA RECEPTOR INHIBITORS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-09-07 | — | — | WO | disclosed |