Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196401 | 0.86 | NPSR1 (0.43) | RORCNPSR1OGAKCNQ3KCNQ2 | |
| SCHEMBL5135180 | 0.85 | RORC (0.45) | RORCENPP2CCR1 | |
| SCHEMBL3200068 | 0.84 | RORC (0.47) | RORCNPSR1 | |
| SCHEMBL3214027 | 0.84 | RORC (0.47) | RORCNPSR1 | |
| SCHEMBL3208737 | 0.84 | RORC (0.47) | RORCNPSR1 | |
| SCHEMBL3201129 | 0.82 | RORC (0.48) | RORCKCNH2ENPP2CCR1 | |
| SCHEMBL402294 | 0.81 | NPSR1 (0.41) | RORCNPSR1KCNQ3KCNQ2 | |
| SCHEMBL3214394 | 0.77 | RORC (0.47) | RORCNPSR1 | |
| SCHEMBL3209497 | 0.77 | RORC (0.47) | RORCNPSR1 | |
| SCHEMBL3191043 | 0.76 | RORC (0.46) | RORCNPSR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959960-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007070683-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |