SCHEMBL5137409

SCHEMBL5137409

CCCCC(CC)CN(CCCC)CCC(=O)OCC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.51
TSHR P16473 3/20 0.51
ATM Q13315 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CA2 P00918 4/20 0.41
RECQL P46063 1/20 0.38
ALDH1A1 P00352 5/20 0.38
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.37
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
CA1 P00915 1/20 0.35
DNM1 Q05193 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5138312 0.94 TSHR (0.49) CYP3A4TSHRATMTDP1CA2
SCHEMBL5139117 0.94 CYP3A4 (0.54) CYP3A4TSHRATMTDP1CA2
SCHEMBL5137961 0.90 CYP3A4 (0.66) CYP3A4TSHRATMTDP1CA2
SCHEMBL5137769 0.90 CYP3A4 (0.50) CYP3A4TSHRATMTDP1CA2
SCHEMBL5138347 0.85 CYP3A4 (0.48) CYP3A4TSHRATMTDP1CA2
SCHEMBL5138591 0.84 CYP3A4 (0.69) CYP3A4TSHRATMTDP1CA2
SCHEMBL5077574 0.82 CYP3A4 (0.50) CYP3A4TSHRATMTDP1CA2
SCHEMBL19478720 0.81 CYP1A2 (0.48) CYP3A4ALDH1A1LMNACYP1A2CA1
SCHEMBL8466798 0.81 CYP1A2 (0.48) CYP3A4ALDH1A1LMNACYP1A2CA1
SCHEMBL25206839 0.80 TSHR (0.44) CYP3A4TSHRATMTDP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965639-A1 INSECT REPELLENT MIXTURE Merck Patent GmbH (DE) 2008-09-10 EP disclosed
WO-2007079822-A1 INSECT REPELLENT MIXTURE MERCK PATENT GMBH (DE) 2007-07-19 WO disclosed
EP-1725520-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLIGICAL PREPARATIONS MERCK PATENT GmbH (DE) 2006-11-29 EP disclosed
WO-2005074897-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLOGICAL PREPARATIONS MERCK PATENT GMBH (DE) 2005-08-18 WO disclosed