SCHEMBL5138591

SCHEMBL5138591

CCCCC(CC)COC(=O)CCN(CC(CC)CCCC)CC(CC)CCCC

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.69
TSHR P16473 3/20 0.69
ATM Q13315 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
RECQL P46063 1/20 0.51
ALDH1A1 P00352 5/20 0.47
CA2 P00918 3/20 0.47
LMNA P02545 3/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPK1 P28482 2/20 0.43
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.40
PRKCA P17252 1/20 0.39
PRKCE Q02156 1/20 0.39
PRKCQ Q04759 1/20 0.39
PRKCD Q05655 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5137961 0.94 CYP3A4 (0.66) CYP3A4TSHRATMTDP1RECQL
SCHEMBL15015605 0.91 CYP3A4 (0.73) CYP3A4TSHRATMTDP1RECQL
SCHEMBL5139117 0.90 CYP3A4 (0.54) CYP3A4TSHRATMTDP1RECQL
SCHEMBL9064848 0.90 CYP3A4 (0.71) CYP3A4TSHRATMTDP1RECQL
SCHEMBL27268370 0.87 CYP3A4 (0.68) CYP3A4TSHRATMTDP1RECQL
SCHEMBL27266900 0.87 CYP3A4 (0.68) CYP3A4TSHRATMTDP1RECQL
SCHEMBL427850 0.87 CYP3A4 (0.68) CYP3A4TSHRATMTDP1RECQL
SCHEMBL9942321 0.86 CYP3A4 (0.66) CYP3A4TSHRATMTDP1RECQL
SCHEMBL28527517 0.86 CYP3A4 (0.66) CYP3A4TSHRATMTDP1RECQL
SCHEMBL27268115 0.86 CYP3A4 (0.66) CYP3A4TSHRATMTDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1965639-A1 INSECT REPELLENT MIXTURE Merck Patent GmbH (DE) 2008-09-10 EP claimed
WO-2007079822-A1 INSECT REPELLENT MIXTURE MERCK PATENT GMBH (DE) 2007-07-19 WO claimed
EP-1725520-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLIGICAL PREPARATIONS MERCK PATENT GmbH (DE) 2006-11-29 EP claimed
WO-2005074897-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLOGICAL PREPARATIONS MERCK PATENT GMBH (DE) 2005-08-18 WO claimed
EP-1965639-A1 INSECT REPELLENT MIXTURE Merck Patent GmbH (DE) 2008-09-10 EP disclosed
WO-2007079822-A1 INSECT REPELLENT MIXTURE MERCK PATENT GMBH (DE) 2007-07-19 WO disclosed
EP-1725520-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLIGICAL PREPARATIONS MERCK PATENT GmbH (DE) 2006-11-29 EP disclosed
WO-2005074897-A2 FORMULATION AUXILIARY AGENTS (AMINOPROPANOIC ACID DERIVATIVE) IN COSMETIC OR DERMATOLOGICAL PREPARATIONS MERCK PATENT GMBH (DE) 2005-08-18 WO disclosed