Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293088 | 0.78 | ALDH1A1 (0.63) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL4544154 | 0.76 | KDM4E (1.00) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL3863268 | 0.76 | KDM4E (0.61) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL173688 | 0.76 | KDM4E (0.61) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL458846 | 0.76 | KDM4E (0.61) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL4912309 | 0.72 | KDM4E (0.56) | KDM4EGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6249816 | 0.72 | KDM4E (0.61) | KDM4EPKMMAPTGRIA1GRIA2 | |
| SCHEMBL20945207 | 0.72 | KDM4E (0.61) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL4057148 | 0.72 | KDM4E (0.61) | KDM4EMAPTGRIA1GRIA2GRIA3 | |
| SCHEMBL9731221 | 0.72 | KDM4E (0.56) | KDM4EMAPTGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| WO-2007017264-A2 | PYRROLOPYRIDINEDERIVATIVES AS MODULATORS OF THE CANNABINOID RECEPTOR FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS | GLAXO GROUP LIMITED (GB) | 2007-02-15 | — | — | WO | disclosed |