Eugenyl Acetate

Eugenyl Acetate

SCHEMBL5138181

C=CCc1ccc(O)c(OC)c1.C=CCc1ccc(OC(C)=O)c(OC)c1.CC(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Eugenyl Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.82
ALDH1A1 P00352 4/20 0.70
ALOX5 P09917 4/20 0.70
CYP3A4 P08684 2/20 0.70
AR P10275 1/20 0.70
TRPM8 Q7Z2W7 1/20 0.70
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
TDP1 Q9NUW8 2/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
MAOA P21397 1/20 0.60
MAOB P27338 1/20 0.60
PPARA Q07869 3/20 0.58
PPARG P37231 1/20 0.58
PPARD Q03181 1/20 0.58
GABRA1 P14867 2/20 0.56
GABRB2 P47870 2/20 0.56
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
PRSS1 P07477 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eugenyl Acetate SCHEMBL26667569 0.97 PTGS1 (0.87) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenol SCHEMBL27608718 0.91 ALDH1A1 (0.85) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenyl Acetate SCHEMBL29802968 0.91 PTGS1 (1.00) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenol SCHEMBL114133 0.91 ALDH1A1 (0.85) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenyl Acetate SCHEMBL14764089 0.91 PTGS1 (1.00) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenyl Acetate SCHEMBL112232 0.91 PTGS1 (1.00) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenol SCHEMBL29943804 0.91 ALDH1A1 (0.85) PTGS1ALDH1A1ALOX5CYP3A4AR
Eugenol SCHEMBL27710638 0.90 ALDH1A1 (0.82) PTGS1ALDH1A1ALOX5CYP3A4AR
Acetic Acid SCHEMBL2450520 0.90 PTGS1 (0.68) PTGS1ALDH1A1ALOX5CYP3A4AR
SCHEMBL4254460 0.87 PTGS1 (0.71) PTGS1ALDH1A1ALOX5CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323187-B1 Impregnation method SCHUER JOERG PETER 2008-01-29 US disclosed