Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138502 | 0.92 | TGFBR1 (0.40) | TGFBR1MAPK14 | |
| SCHEMBL5200543 | 0.88 | TGFBR1 (0.53) | TGFBR1MAPK14 | |
| Hydroxyamine SCHEMBL5321623 | 0.82 | TGFBR1 (0.39) | TGFBR1MAPK14 | |
| SCHEMBL4336673 | 0.81 | TGFBR1 (0.62) | TGFBR1MAPK14 | |
| SCHEMBL4336656 | 0.80 | TGFBR1 (0.56) | TGFBR1MAPK14 | |
| SCHEMBL4339426 | 0.79 | TGFBR1 (0.54) | TGFBR1MAPK14 | |
| SCHEMBL4332553 | 0.79 | TGFBR1 (0.55) | TGFBR1MAPK14 | |
| SCHEMBL4345065 | 0.77 | TGFBR1 (0.41) | TGFBR1MAPK14 | |
| SCHEMBL21447801 | 0.77 | TGFBR1 (0.51) | TGFBR1MAPK14 | |
| SCHEMBL4339269 | 0.74 | TGFBR1 (0.42) | TGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786802-A1 | PYRIMIDINYLIMIDAZOLES AS TGF-BETA INHIBITORS | Biogen Idec MA, Inc. (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006026306-A1 | PYRIMIDINYLIMIDAZOLES AS TGF-BETA INHIBITORS | BIOGEN IDEC MA INC. (US) | 2006-03-09 | — | — | WO | claimed |
| WO-2008013928-A2 | TREATMENT OF CANCER WITH INTERFERON GENE DELIVERY IN COMBINATION WITH A TGF-BETA INHIBITOR | BIOGEN IDEC MA INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| EP-1786802-A1 | PYRIMIDINYLIMIDAZOLES AS TGF-BETA INHIBITORS | Biogen Idec MA, Inc. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006026306-A1 | PYRIMIDINYLIMIDAZOLES AS TGF-BETA INHIBITORS | BIOGEN IDEC MA INC. (US) | 2006-03-09 | — | — | WO | disclosed |