Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | GALK1 | P51570 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | S100A4 | P26447 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17330278 | 0.88 | LMNA (0.53) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL17347333 | 0.85 | KDM4E (0.57) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL11848796 | 0.81 | NQO1 (0.56) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL30272141 | 0.80 | LMNA (0.67) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL17844954 | 0.80 | LMNA (1.00) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL2017838 | 0.80 | LMNA (0.67) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL21645618 | 0.80 | LMNA (0.67) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL3680356 | 0.80 | LMNA (0.67) | LMNAMAPTKMT2AMEN1GAA | |
| SCHEMBL11852487 | 0.80 | CA9 (0.68) | LMNAMAPTKMT2AMEN1POLB | |
| SCHEMBL27886686 | 0.79 | CSNK2A2 (0.52) | LMNAMAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108598533-B | Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof | 同济大学 | 2020-11-03 | — | — | CN | claimed |
| US-9870909-B2 | Compositions and methods for mass spectometry | MSTM, LLC | 2018-01-16 | — | — | US | claimed |
| US-12486293-B2 | Chirality sensing with molecular click chemistry probes | GEORGETOWN UNIVERSITY (US) | 2025-12-02 | — | — | US | disclosed |
| CN-118834490-A | Photo-crosslinkable perfluorinated ion membrane and preparation method thereof | 上海交通大学 | 2024-10-25 | — | — | CN | disclosed |
| US-20220380395-A1 | CHIRALITY SENSING WITH MOLECULAR CLICK CHEMISTRY PROBES | GEORGETOWN UNIVERSITY | 2022-12-01 | — | — | US | disclosed |
| CN-108598533-B | Coumarin-based photocyclization crosslinking sulfonated polyimide proton exchange membrane and preparation method thereof | 同济大学 | 2020-11-03 | — | — | CN | disclosed |
| WO-2020028396-A1 | CHIRALITY SENSING WITH MOLECULAR CLICK CHEMISTRY PROBES | GEORGETOWN UNIVERSITY (US) | 2020-02-06 | — | — | WO | disclosed |
| US-9870909-B2 | Compositions and methods for mass spectometry | MSTM, LLC | 2018-01-16 | — | — | US | disclosed |
| US-9870909-B2 | Compositions and methods for mass spectometry | MSTM, LLC | 2018-01-16 | — | — | US | disclosed |
| US-20150364311-A1 | COMPOSITIONS AND METHODS FOR MASS SPECTOMETRY | MSTM, LLC | 2015-12-17 | — | — | US | disclosed |
| CN-105017195-A | 4-hydroxycoumarin-3-Schiff base derivate and use thereof for curing Alzheimer's disease | UNIV CHINA PHARMA | 2015-11-04 | — | — | CN | disclosed |
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | disclosed |
| US-4716222-A | CHROMOGENS, SPECTROPHOTOMETRY | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| EP-0157384-A2 | Substrates for hydrolases, process for their preparation and their use | Biomed Labordiagnostik GmbH (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0050396-B1 | COUMARIN INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-12-27 | — | — | EP | disclosed |
| EP-0010392-B1 | HETEROCYCLIC COUMARIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID DERIVATIVES | BEECHAM GROUP PLC (GB) | 1982-12-29 | — | — | EP | disclosed |
| EP-0050396-A1 | Coumarin intermediates | BEECHAM GROUP PLC (GB) | 1982-04-28 | — | — | EP | disclosed |
| US-3974289-A | Coumarin derivatives for the treatment of allergies | BEECHAM GROUP LIMITED (EN) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | LMNA 4191/4885MAPT 4566/4885KMT2A 4362/4885 |
| US-20220380395-A1 | CHIRALITY SENSING WITH MOLECULAR CLICK CHEMISTRY PROBES | PTMS, NISCH, CHAMP1 | LMNA 2928/4885MAPT 4815/4885KMT2A 4568/4885 |
| US-12486293-B2 | Chirality sensing with molecular click chemistry probes | PTMS, NISCH, CHAMP1 | LMNA 2928/4885MAPT 4815/4885KMT2A 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.