Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734958 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL27678203 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL9752654 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL19304404 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL16115136 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL15573513 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL28390769 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL15376927 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL1325052 | 0.98 | TDP1 (0.48) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL4412197 | 0.92 | CYP2D6 (0.43) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300342-A1 | Polyolefin Resin Composition and Electric Wire Using the Same | YAZAKI CORPORATION | 2008-12-04 | — | — | US | disclosed |