Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678203 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL9752654 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL19304404 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL16115136 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL15573513 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL5138548 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL28390769 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL15376927 | 1.00 | TDP1 (0.47) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL1325052 | 0.98 | TDP1 (0.48) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 | |
| SCHEMBL4412197 | 0.92 | CYP2D6 (0.43) | TDP1L3MBTL1KCNH2KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373817-A1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | Astrazeneca AB (SE) | 2024-05-29 | — | — | EP | disclosed |
| US-11993674-B2 | Functional resin material, manufacturing method thereof, and moisture-sensed shrinking fabric | TAIWAN TEXTILE RESEARCH INSTITUTE (TW) | 2024-05-28 | — | — | US | disclosed |
| EP-2775839-B1 | METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | UNIV CALIFORNIA (US) | 2023-12-06 | — | — | EP | disclosed |
| WO-2023001794-A1 | SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2023-01-26 | — | — | WO | disclosed |
| US-20220010050-A1 | FUNCTIONAL RESIN MATERIAL, MANUFACTURING METHOD THEREOF, AND MOISTURE-SENSED SHRINKING FABRIC | TAIWAN TEXTILE RESEARCH INSTITUTE (TW) | 2022-01-13 | — | — | US | disclosed |
| US-10308975-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | PROMEGA CORPORATION (US) | 2019-06-04 | — | — | US | disclosed |
| US-20180223330-A1 | COELENTERAZINE ANALOGUES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
| EP-2067782-B2 | HETEROACENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND THEIR PRODUCTION METHODS | TOSOH CORP (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-9963450-B2 | A3 adenosine receptor agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-08 | — | — | US | disclosed |
| EP-2775839-A2 | METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | The Regents of The University of California (US) | 2014-09-17 | — | — | EP | disclosed |
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | MORRIELLO GREGORI J | 2008-11-13 | — | — | US | disclosed |
| EP-1587863-A1 | NETWORK SILICA FOR ENHANCING TENSILE STRENGTH OF RUBBER COMPOUND | Republic of Korea (Chonnam National University) (KR) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004078835-A1 | NETWORK SILICA FOR ENHANCING TENSILE STRENGTH OF RUBBER COMPOUND | REPUBLIC OF KOREA(CHONNAM NATIONAL UNIVERSITY) (KR) | 2004-09-16 | — | — | WO | disclosed |
| EP-0637323-B1 | COPOLYMERS AND NON-POROUS, SEMI-PERMEABLE MEMBRANE THEREOF AND ITS USE FOR PERMEATING MOLECULES OF PREDETERMINED MOLECULAR WEIGHT RANGE | POLYMER TECHNOLOGY GROUP INC (US) | 1998-08-19 | — | — | EP | disclosed |
| US-5403877-A | Salts of triazine derivatives with oxygenated acids of phosphorus and their use in self-extinguishing polymeric compositions | MINISTERO DELL'UNIVERSITA E DELLA RICERCA SCIENTIFICA E. TECNOLOGICA (IT) | 1995-04-04 | — | — | US | disclosed |
| US-4871848-A | OIL, GAS WELLS CORROSION INHIBITORS | THE DOW CHEMICAL COMPANY (US) | 1989-10-03 | — | — | US | disclosed |
| US-4740320-A | REACTION OF NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPONENT, KETONE OR ALDEHYDE, AMINE OR POLYAMINE | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4725373-A | CORROSION RESISTANCE FOR METAL TOOLS AND EQUIPMENT USED IN OIL AND GAS WELLS | THE DOW CHEMICAL COMPANY (US) | 1988-02-16 | — | — | US | disclosed |
| US-4724003-A | Asphalt compositions containing anti-stripping additives prepared from hydrocarbyl substituted nitrogen-containing aromatic heterocyclic compounds, aldehydes or ketones and amines | THE DOW CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4676834-A | Novel compositions prepared from methyl substituted nitrogen-containing aromatic heterocyclic compounds and an aldehyde or ketone | THE DOW CHEMICAL COMPANY (US) | 1987-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | APOB, PCSK9, CYP46A1 | TDP1 4349/4885L3MBTL1 3411/4885KCNH2 500/4885 |
| US-20180223330-A1 | COELENTERAZINE ANALOGUES | GLB1, SI, TCF7L2 | TDP1 3852/4885L3MBTL1 52/4885KCNH2 1711/4885 |
| US-10308975-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | AADAC, PGLS, GLB1 | TDP1 3491/4885L3MBTL1 241/4885KCNH2 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.