Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015605 | 0.92 | CYP3A4 (0.73) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL5138591 | 0.90 | CYP3A4 (0.69) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL27268370 | 0.88 | CYP3A4 (0.68) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL27266900 | 0.88 | CYP3A4 (0.68) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL427850 | 0.88 | CYP3A4 (0.68) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL28527517 | 0.87 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL5137961 | 0.87 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL9942321 | 0.87 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL27268115 | 0.87 | CYP3A4 (0.66) | CYP3A4TSHRATMTDP1RECQL | |
| SCHEMBL11668677 | 0.86 | CYP3A4 (0.73) | CYP3A4TSHRATMTDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612310-B1 | PROCESS FOR THE MANUFACTURE OF CINNAMIC ACID DERIVATIVES | GIVAUDAN ROURE INT (CH) | 1996-10-16 | — | — | EP | disclosed |
| US-5457226-A | Process for the manufacture of cinnamic acid derivatives | GIVAUDAN-ROURE CORPORATION (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0612310-A1 | PROCESS FOR THE MANUFACTURE OF CINNAMIC ACID DERIVATIVES. | GIVAUDAN ROURE INT (CH) | 1994-08-31 | — | — | EP | disclosed |
| WO-1994005621-A1 | PROCESS FOR THE MANUFACTURE OF CINNAMIC ACID DERIVATIVES | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1994-03-17 | — | — | WO | disclosed |