Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | FPR3 | P25089 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189295 | 0.88 | CRHR1 (0.37) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL4189300 | 0.87 | HTT (0.38) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL27613752 | 0.84 | CRHR1 (0.37) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL27613714 | 0.84 | CRHR1 (0.37) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL12593337 | 0.84 | CRHR1 (0.39) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL12534767 | 0.83 | CRHR1 (0.35) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1039739 | 0.83 | MAP2K7 (0.45) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL29482249 | 0.83 | MAP2K7 (0.45) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL1636914 | 0.83 | CRHR1 (0.35) | CRHR1FPR3TSPOTMEM97 | |
| Hydrochloric Acid SCHEMBL1637180 | 0.82 | MAP2K7 (0.44) | CRHR1FPR3TSPOTMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467997-B8 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO LTD (JP) | 2008-08-27 | — | — | EP | claimed |
| EP-1467997-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-20 | — | — | EP | claimed |
| WO-2004058767-A1 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-15 | — | — | WO | claimed |