Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742752 | 0.95 | HDAC4 (0.44) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3868254 | 0.91 | HDAC4 (0.42) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1018309 | 0.87 | NPC1 (0.47) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1020368 | 0.85 | NPC1 (0.48) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1627286 | 0.83 | ALDH1A1 (0.38) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL26240501 | 0.83 | HDAC4 (0.38) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25389655 | 0.82 | HDAC4 (0.37) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL625354 | 0.82 | NPC1 (0.44) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3533872 | 0.80 | ALDH1A1 (0.37) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL18742611 | 0.78 | BACE1 (0.36) | HDAC4NPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976513-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | Sepracor, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007081857-A2 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2007-07-19 | — | — | WO | disclosed |