⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973891 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL101280 | 0.81 | — | — | |
| SCHEMBL11025503 | 0.79 | — | — | |
| Charcoal, Activated SCHEMBL7916448 | 0.78 | — | — | |
| SCHEMBL28491261 | 0.78 | — | — | |
| Phosphine SCHEMBL28626874 | 0.78 | — | — | |
| Ethyne SCHEMBL7258726 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL3627376 | 0.75 | ALDH1A1 (0.35) | — | |
| SCHEMBL183654 | 0.74 | — | — | |
| SCHEMBL10766856 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384974-B2 | 4,5-dihydronaphtho[1,2-b]thiophene derivative | TAISHA PHARMACEUTICAL CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20060189678-A1 | effective in reducing triglyceride levels in the liver and reducing blood glucose levels | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1650202-A1 | 4,5-DIHYDRONAPHTHO [1,2-b] THIOPHENE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2006-04-26 | — | — | EP | disclosed |