Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139651 | 1.00 | CTSK (0.55) | CTSKCTSSITGAVITGB6NOD1 | |
| SCHEMBL15304810 | 0.90 | CTSK (0.53) | CTSKCTSSITGAVITGB6PPARA | |
| SCHEMBL15243753 | 0.90 | CTSK (0.53) | CTSKCTSSITGAVITGB6PPARA | |
| SCHEMBL14820490 | 0.90 | CTSK (0.62) | CTSKCTSSNOD1MEN1GAA | |
| SCHEMBL18875931 | 0.90 | CTSK (0.62) | CTSKCTSSNOD1MEN1GAA | |
| SCHEMBL3233192 | 0.90 | CTSK (0.62) | CTSKCTSSNOD1MEN1GAA | |
| SCHEMBL17356699 | 0.88 | CTSK (0.60) | CTSKCTSSNOD1 | |
| SCHEMBL16939058 | 0.88 | CTSK (0.60) | CTSKCTSSNOD1 | |
| SCHEMBL7547354 | 0.88 | CTSK (0.60) | CTSKCTSSNOD1 | |
| SCHEMBL9743599 | 0.88 | CTSK (0.60) | CTSKCTSSNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951743-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007056120-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |