Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960765 | 1.00 | MAPT (0.52) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL4962623 | 1.00 | MAPT (0.52) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL652994 | 1.00 | MAPT (0.52) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL8512702 | 0.96 | MAPT (0.55) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL9137960 | 0.96 | MAPT (0.55) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL8512700 | 0.96 | MAPT (0.55) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL11073044 | 0.96 | MAPT (0.55) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL3060466 | 0.90 | MAPT (0.47) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL8892883 | 0.86 | NT5E (0.46) | MAPTPOLBKMT2AMEN1USP2 | |
| SCHEMBL8892887 | 0.86 | NT5E (0.46) | MAPTPOLBKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421100-B1 | CHEMICAL SYNTHESIS OF SOLAMARGINE | GLYCOMED SCIENCES LTD (KY) | 2008-07-09 | — | — | EP | disclosed |
| US-20040259814-A1 | Synthesis of solanum glycosides | GLYCOMED SCIENCES LIMITED (KY) | 2004-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259814-A1 | Synthesis of solanum glycosides | GALE, MGAM, STS | MAPT 3697/4885POLB 4405/4885KMT2A 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.