Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 3/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892883 | 1.00 | NT5E (0.46) | NT5EMAPTKMT2ASLC6A2SLC6A3 | |
| SCHEMBL4960765 | 0.86 | MAPT (0.52) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL5139788 | 0.86 | MAPT (0.52) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL652994 | 0.86 | MAPT (0.52) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL4962623 | 0.86 | MAPT (0.52) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8512700 | 0.82 | MAPT (0.55) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8512702 | 0.82 | MAPT (0.55) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL9137960 | 0.82 | MAPT (0.55) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL11073044 | 0.82 | MAPT (0.55) | MAPTKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL8373150 | 0.78 | NT5E (0.53) | NT5EKMT2ASLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658880-A | PREVENT SELECTIN BINDING; ANTIINFLAMMATORY, ANTICANCER AGENTS; AIDS THERAPY | GLYCOMED INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |