Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17510159 | 0.88 | HTT (0.34) | HTT | |
| SCHEMBL10442768 | 0.87 | HTT (0.38) | HTT | |
| SCHEMBL5132938 | 0.86 | POLB (0.41) | HTT | |
| SCHEMBL10442725 | 0.84 | — | — | |
| SCHEMBL2601280 | 0.83 | ATM (0.37) | — | |
| SCHEMBL2601251 | 0.83 | HTT (0.37) | HTT | |
| SCHEMBL2600940 | 0.83 | CHRM1 (0.38) | — | |
| SCHEMBL20014654 | 0.80 | HTT (0.46) | HTTPARP1PARP2 | |
| SCHEMBL4154708 | 0.78 | — | — | |
| SCHEMBL2601001 | 0.78 | LIPG (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1950212-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING INHIBITORY ACTIVITY ON HIV INTEGRASE | SHIONOGI & CO (JP) | 2016-02-24 | — | — | EP | disclosed |
| EP-1950212-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING INHIBITORY ACTIVITY ON HIV INTEGRASE | Shionogi Co., Ltd. (JP) | 2008-07-30 | — | — | EP | disclosed |