Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337212 | 0.68 | CYP2A6 (0.42) | — | |
| SCHEMBL28277235 | 0.68 | HTT (0.42) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL16391314 | 0.68 | MEN1 (0.40) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL11189202 | 0.64 | CYP2A6 (0.38) | — | |
| SCHEMBL28548627 | 0.62 | MEN1 (0.45) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL28438701 | 0.61 | TTR (0.61) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL17188021 | 0.61 | HTT (0.46) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL18585266 | 0.61 | CYP2A6 (0.50) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL25242609 | 0.60 | MEN1 (0.42) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL18585154 | 0.60 | XDH (0.45) | MEN1TTRALBKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954287-A2 | CETP INHIBITORS | Merck & Co., Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007070173-A2 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2007-06-21 | — | — | WO | disclosed |