Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 13/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129882 | 1.00 | CETP (0.40) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL1588345 | 0.92 | CETP (0.47) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL1587728 | 0.89 | CETP (0.37) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL1588012 | 0.87 | CETP (0.41) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL1587625 | 0.87 | MGLL (0.41) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL134654 | 0.85 | CETP (0.42) | CETPPPARGPPARDPPARAPDK2 | |
| SCHEMBL1588203 | 0.84 | CETP (0.44) | CETPMGLLPPARGPPARDPPARA | |
| SCHEMBL1588147 | 0.84 | CETP (0.41) | CETPPPARGPPARDPPARAPDK2 | |
| SCHEMBL1587666 | 0.83 | GPBAR1 (0.47) | CETPPDK2 | |
| SCHEMBL1587427 | 0.83 | CETP (0.41) | CETPPPARGPPARDPPARAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979331-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |