Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312493 | 0.94 | PIK3CD (0.45) | RIPK1PIK3CD | |
| SCHEMBL14313418 | 0.92 | PIK3CD (0.45) | RIPK1PIK3CD | |
| SCHEMBL14312945 | 0.90 | PIK3CD (0.44) | RIPK1PIK3CD | |
| SCHEMBL14312688 | 0.90 | RIPK1 (0.43) | RIPK1PIK3CD | |
| SCHEMBL5074942 | 0.89 | PIK3CD (0.51) | RIPK1PIK3CD | |
| SCHEMBL5074925 | 0.89 | PIK3CD (0.43) | RIPK1PIK3CD | |
| SCHEMBL5076815 | 0.88 | PIK3CD (0.50) | RIPK1PIK3CD | |
| SCHEMBL14312965 | 0.88 | RIPK1 (0.42) | RIPK1PIK3CD | |
| SCHEMBL14312905 | 0.88 | PIK3CD (0.55) | RIPK1PIK3CD | |
| SCHEMBL14312843 | 0.88 | RIPK1 (0.43) | RIPK1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945222-A2 | PYRROLO[2,1-F] [1,2,4] TRIAZIN-4-YLAMINES IGF-1R KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER HYPERPROLIFERATIVE DISEASES | Bayer HealthCare AG (DE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056170-A2 | PYRROLO[2,1-F] [1,2,4] TRIAZIN-4-YLAMINES IGF-1R KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER HYPERPROLIFERATIVE DISEASES | BAYER HEALTHCARE AG (DE) | 2007-05-18 | — | — | WO | disclosed |