Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141112 | 0.89 | PPARG (0.36) | POLBPPARGMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30932837 | 0.80 | POLB (0.52) | POLBSLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL866279 | 0.80 | POLB (0.52) | POLBSLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL11482869 | 0.71 | POLB (0.59) | POLBSLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL864911 | 0.71 | IDO1 (0.47) | PPARGMAPTALDH1A1TSHRMAPK1 | |
| SCHEMBL1656268 | 0.70 | NSD2 (0.46) | PPARGALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL3357437 | 0.65 | PDE7A (0.58) | POLBSLC6A4MAPTLMNASMN1; SMN2 | |
| SCHEMBL14784951 | 0.64 | IDO1 (0.40) | MAPTALDH1A1TACR1TSHRMAPK1 | |
| SCHEMBL550610 | 0.63 | SKP2 (0.45) | POLBPPARGMAPTRAB9AALDH1A1 | |
| SCHEMBL28904169 | 0.62 | IDO1 (0.46) | POLBPPARGALDH1A1CYP3A4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966119-A1 | PHOTOCROSSLINKABLE MATERIALS | Rolic AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071091-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2007-06-28 | — | — | WO | disclosed |