SCHEMBL866279

SCHEMBL866279

Cc1cc(C)c(CSc2ccccc2N)c(C)c1CSc1ccccc1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.52
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 2/20 0.43
MAPT P10636 2/20 0.43
HIF1A Q16665 1/20 0.43
SLC11A2 P49281 1/20 0.43
CYP3A4 P08684 3/20 0.43
NPSR1 Q6W5P4 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
SLC6A4 P31645 4/20 0.40
SLC6A2 P23975 3/20 0.40
SLC6A3 Q01959 2/20 0.40
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932837 1.00 POLB (0.52) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL11482869 0.89 POLB (0.59) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL5141111 0.80 POLB (0.38) POLBSMN1; SMN2NPC1RAB9ACYP1A2
SCHEMBL16242607 0.76 POLB (0.57) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL21608867 0.72 SLC6A4 (0.49) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL16242574 0.72 POLB (0.68) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL8378911 0.70 POLB (0.71) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL16242814 0.70 POLB (0.65) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL16242598 0.70 POLB (0.87) POLBMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL16242699 0.69 POLB (0.77) POLBMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 US disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 US disclosed
EP-3374467-B1 COMPOSITIONS OF PHOTO-ALIGNABLE MATERIALS ROLIC TECH AG (CH) 2020-04-15 EP disclosed
US-10558089-B2 Photoalignment composition ROLIC AG (CH) 2020-02-11 US disclosed
EP-2222815-B1 PHOTOALIGNMENT COMPOSITION ROLIC TECH AG (CH) 2019-05-29 EP disclosed
WO-2011003981-A2 COMPOSITION MADE FROM NATURAL RUBBER AND A POLYIMINE COMPOUND SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-01-13 WO disclosed
WO-2011003983-A1 COMPOSITION BASED ON NATURAL RUBBER AND A POLYAMINE COMPOUND SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-01-13 WO disclosed
WO-2011003982-A1 COMPOSITION BASED ON NATURAL RUBBER AND A POLYIMINE COMPOUND SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2011-01-13 WO disclosed
US-20100266814-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2010-10-21 US disclosed
EP-2222815-A1 PHOTOALIGNMENT COMPOSITION Rolic Ltd. (CH) 2010-09-01 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
WO-2009080271-A1 PHOTOALIGNMENT COMPOSITION ROLIC LTD. (CH) 2009-07-02 WO disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
US-20080293888-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 POLB 794/4885MEN1 2579/4885KMT2A 770/4885
US-20080293888-A1 Photocrosslinkable Materials DDC, PARG, ALAD POLB 723/4885MEN1 676/4885KMT2A 666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.