SCHEMBL5141933

SCHEMBL5141933

COc1ccccc1Oc1ccc2c(O)c(C(=O)N[C@@H](C)C(=O)O)ncc2c1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 17/20 0.55
EGLN1 Q9GZT9 16/20 0.55
BBOX1 O75936 2/20 0.47
FTO Q9C0B1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5141932 1.00 EGLN2 (0.55) EGLN2EGLN1BBOX1FTO
SCHEMBL30402374 0.89 EGLN2 (0.68) EGLN2EGLN1
SCHEMBL964665 0.89 EGLN2 (0.68) EGLN2EGLN1
SCHEMBL522778 0.89 EGLN2 (0.68) EGLN2EGLN1
SCHEMBL522777 0.89 EGLN2 (0.68) EGLN2EGLN1
SCHEMBL523001 0.88 EGLN2 (0.70) EGLN2EGLN1
SCHEMBL523000 0.88 EGLN2 (0.70) EGLN2EGLN1
SCHEMBL523441 0.85 EGLN2 (0.58) EGLN2EGLN1
SCHEMBL523442 0.85 EGLN2 (0.58) EGLN2EGLN1
SCHEMBL523565 0.83 EGLN2 (0.58) EGLN2EGLN1BBOX1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070293575-A1 Compounds and methods for treatment of cancer-related anemia FIBROGEN, INC. (US) 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070293575-A1 Compounds and methods for treatment of cancer-related anemia EPOR, THPO, TFRC EGLN2 11/4885EGLN1 21/4885BBOX1 1307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.