Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.41 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144279 | 0.81 | DAO (0.41) | PARP1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL3295739 | 0.79 | CYP1A2 (0.49) | LMNANR1H2NR1H3CYP11B2NR4A2 | |
| SCHEMBL5145732 | 0.78 | NR1H2 (0.41) | LMNANR1H2NR1H3PIK3R2CYP11B2 | |
| SCHEMBL5144181 | 0.78 | DAO (0.39) | LMNACYP11B2KDM4EMEN1NPC1 | |
| SCHEMBL28810928 | 0.77 | KDM4E (0.53) | LMNACYP11B2KDM4EMEN1NPC1 | |
| SCHEMBL1271081 | 0.72 | NR1H2 (0.57) | LMNANR1H2NR1H3PIK3R2MEN1 | |
| SCHEMBL1272263 | 0.71 | NR1H2 (0.56) | NR1H2NR1H3PIK3R2 | |
| SCHEMBL3285105 | 0.68 | HTT (0.55) | LMNAKDM4EMEN1NPC1RAB9A | |
| SCHEMBL31746866 | 0.68 | PDE2A (0.42) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1272301 | 0.67 | NR1H2 (0.65) | NR1H2NR1H3PIK3R2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | CDH1, VIL1, TET1 | LMNA 8/4885NR1H2 4335/4885NR1H3 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.