SCHEMBL514221

SCHEMBL514221

[CH2]OCc1cccc(SC(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.44
PTPRZ1 P23471 4/20 0.41
CETP P11597 2/20 0.40
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
PTPN1 P18031 2/20 0.38
IDO1 P14902 4/20 0.38
RXFP1 Q9HBX9 2/20 0.34
UBE2M P61081 1/20 0.34
DCUN1D1 Q96GG9 1/20 0.34
AGXT P21549 3/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PRKCA P17252 1/20 0.33
PRKCD Q05655 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514222 0.83 CETP (0.44) FFAR4PTPRZ1CETPPTPN1IDO1
SCHEMBL17288832 0.81 FFAR4 (0.39) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL5422754 0.80 PTPRZ1 (0.41) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL514240 0.79 FFAR4 (0.44) FFAR4PTPRZ1CETPMAPTPTPN1
SCHEMBL514241 0.79 FFAR4 (0.46) FFAR4PTPRZ1CETPMAPTPTPN1
SCHEMBL17288972 0.78 FFAR4 (0.40) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL513845 0.77 PTPRZ1 (0.39) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL3278395 0.77 CETP (0.42) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL4039392 0.77 CETP (0.42) FFAR4PTPRZ1CETPMAPTATM
SCHEMBL934510 0.77 PTPRZ1 (0.41) FFAR4PTPRZ1CETPMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014184071-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
WO-2014184070-A1 MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES SYNGENTA LIMITED (GB) 2014-11-20 WO disclosed
EP-2420493-A1 HALOALKYLSULFONANILIDE DERIVATIVE Nissan Chemical Industries, Ltd. (JP) 2012-02-22 EP disclosed
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-02-02 US disclosed
EP-2336104-A1 ORTHO-SUBSTITUTED HALOALKYLSULFONANILIDE DERIVATIVE AND HERBICIDE Nissan Chemical Industries, Ltd. (JP) 2011-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029187-A1 HALOALKYLSULFONANILIDE DERIVATIVE CBR3, CBR1, HDHD5 FFAR4 2918/4885PTPRZ1 477/4885CETP 4602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.