Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.62 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766069 | 0.87 | PARP10 (0.78) | PARP10PARP15SRD5A2CA1CA2 | |
| SCHEMBL22281 | 0.87 | PARP10 (0.78) | PARP10PARP15SRD5A2CA1CA2 | |
| SCHEMBL5581520 | 0.87 | PARP10 (0.78) | PARP10PARP15SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL9861713 | 0.87 | PARP10 (0.78) | PARP10PARP15SRD5A2CA1CA2 | |
| Hydrochloric Acid SCHEMBL2709951 | 0.84 | PARP10 (0.75) | PARP10PARP15SRD5A2CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL9436485 | 0.84 | PARP10 (0.75) | PARP10PARP15SRD5A2CA1CA2 | |
| Hydrochloric Acid SCHEMBL5042789 | 0.84 | PARP10 (0.75) | PARP10PARP15SRD5A2CA1CA2 | |
| Hydrochloric Acid SCHEMBL9633355 | 0.84 | PARP10 (0.75) | PARP10PARP15SRD5A2CA1CA2 | |
| SCHEMBL5158928 | 0.83 | SRD5A2 (0.55) | PARP10PARP15SRD5A2TSHRKMT2A | |
| Ethane SCHEMBL11219716 | 0.82 | PARP10 (0.72) | PARP10PARP15SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105131289-A | Novel sulfonated polybenzimidazole copolymer, crosslinked membrane, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2015-12-09 | — | — | CN | claimed |
| CN-102219898-B | Poly-schiff base for resistance-type storage material | NINGBO INST MAT TECH & ENG CAS | 2012-10-17 | — | — | CN | claimed |
| EP-1786421-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | Cengent Therapeutics, Inc. (US) | 2007-05-23 | — | — | EP | claimed |
| US-20060135483-A1 | Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2006-06-22 | — | — | US | claimed |
| WO-2006017124-A2 | OXYGEN/NITROGEN HETEROCYCLE INHIBITORS OF TYROSINE PHOSPHATASES | CENGENT THERAPEUTICS, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| CN-109806912-B | Neodymium complex/GO/Fe capable of being magnetically recycled3O4Ternary complex and preparation method and application thereof | 山西大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-104822444-B | Gas separation membrane | 中央硝子株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-103561852-B | Gas separation membrane | CENTRAL GLASS CO.,LTD. (JP) | 2016-03-30 | — | — | CN | disclosed |
| CN-103562261-B | Fluoropolymer monomer and use its macromolecular compound | CENTRAL GLASS CO.,LTD. (JP) | 2016-03-16 | — | — | CN | disclosed |
| CN-105131289-A | Novel sulfonated polybenzimidazole copolymer, crosslinked membrane, preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2015-12-09 | — | — | CN | disclosed |
| CN-104837809-A | Diamine containing hexafluoroisopropanol group, polyimide and polyamide using the same, cyclized product thereof, and method for producing the same | CENTRAL GLASS CO LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-104822445-A | Gas separation membrane | CENTRAL GLASS CO LTD | 2015-08-05 | — | — | CN | disclosed |
| US-20030187042-A1 | NR1H4 nuclear receptor binding compounds | PHENEX PHARMACEUTICALS AG (DE) | 2003-10-02 | — | — | US | disclosed |
| WO-2003015771-A1 | FXR NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS | LION BIOSCIENCE AG (DE) | 2003-02-27 | — | — | WO | disclosed |
| US-5777151-A | REACTING CARBOXYLIC ACID SALT WITH ORGANIC HALOCOMPOUND USING ONIUM SALT PHASE TRANSFER CATALYST | RHONE-POULENC CHIMIE (FR) | 1998-07-07 | — | — | US | disclosed |
| US-5260475-A | Esterification of hydroxybenzoic acids | RHONE-POULENC CHIMIE (FR) | 1993-11-09 | — | — | US | disclosed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |
| US-4067892-A | HYPOLIPIDEMIC, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1978-01-10 | — | — | US | disclosed |
| US-4067892-A | HYPOLIPIDEMIC, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1978-01-10 | — | — | US | disclosed |
| US-3983164-A | HYPOLIPOLYTIC AND HYPOGLYCEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187042-A1 | NR1H4 nuclear receptor binding compounds | NR1H4, NR1H2, NR1H3 | PARP10 1009/4885PARP15 1099/4885SRD5A2 113/4885 |
| US-20060135483-A1 | Oxygen/nitrogen heterocycle inhibitors of tyrosine phosphatases | PTPRO, PTPRG, PTPN1 | PARP10 4399/4885PARP15 4629/4885SRD5A2 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.