SCHEMBL5158928

SCHEMBL5158928

O=C(c1cc[c]cc1)c1ccc(Oc2cc[c]cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 6/20 0.55
PARP10 Q53GL7 5/20 0.48
HPGD P15428 3/20 0.48
ALDH1A1 P00352 2/20 0.48
PARP15 Q460N3 2/20 0.48
KMT2A Q03164 1/20 0.48
PARP14 Q460N5 1/20 0.48
PARP16 Q8N5Y8 1/20 0.48
PARP11 Q9NR21 1/20 0.48
PARP4 Q9UKK3 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
POLB P06746 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
STS P08842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579976 0.90 SRD5A2 (0.50) SRD5A2PARP10HPGDALDH1A1PARP15
SCHEMBL398594 0.90 SRD5A2 (0.50) SRD5A2PARP10HPGDALDH1A1PARP15
Diphenylether SCHEMBL28544646 0.84 SRD5A2 (0.61) SRD5A2PARP10ALDH1A1KMT2APOLB
SCHEMBL5142268 0.83 PARP10 (0.62) SRD5A2PARP10HPGDALDH1A1PARP15
SCHEMBL1535886 0.82 ALDH1A1 (0.50) SRD5A2HPGDALDH1A1KMT2AMAPT
SCHEMBL2888300 0.82 RXFP1 (0.63) PARP10HPGDALDH1A1KMT2APARP4
SCHEMBL5821870 0.79 SRD5A2 (0.47) SRD5A2PARP10KMT2APOLBSTS
SCHEMBL7753567 0.79 SRD5A2 (0.41) SRD5A2PARP10HPGDALDH1A1PARP15
SCHEMBL5505996 0.79 CA1 (0.60) PARP10HPGDALDH1A1KMT2AMAPT
SCHEMBL609237 0.76 LTA4H (0.44) PARP10HPGDALDH1A1PARP15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1749052-A1 HALOGEN-FREE FLAME RETARDANT POLYAMIDE COMPOSITION WITH IMPROVED ELECTRICAL AND FLAMMABILITY PROPERTIES GENERAL ELECTRIC COMPANY (US) 2007-02-07 EP disclosed
WO-2005118698-A1 HALOGEN-FREE FLAME RETARDANT POLYAMIDE COMPOSITION WITH IMPROVED ELECTRICAL AND FLAMMABILITY PROPERTIES GENERAL ELECTRIC COMPANY (US) 2005-12-15 WO disclosed