Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.58 |
| ▸ | DRD1 | P21728 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.58 |
| ▸ | HRH1 | P35367 | 4/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.58 |
| ▸ | HTR2B | P41595 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12208493 | 0.85 | DRD2 (0.61) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL12227061 | 0.82 | DRD2 (0.62) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL79367 | 0.82 | DRD2 (0.58) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL8490022 | 0.82 | CHRM1 (0.58) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL22076574 | 0.82 | DRD2 (0.58) | DRD2CHRM1DRD1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL937256 | 0.81 | DRD2 (0.57) | DRD2CHRM1DRD1LMNACHRM2 | |
| Hydrochloric Acid SCHEMBL30040103 | 0.81 | DRD2 (0.57) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL8215854 | 0.79 | DRD2 (0.55) | DRD2CHRM1DRD1LMNACHRM2 | |
| SCHEMBL25873330 | 0.75 | CHRM2 (0.51) | DRD2CHRM1DRD1LMNACHRM2 | |
| Olanzapine SCHEMBL28763 | 0.74 | CHRM1 (1.00) | DRD2CHRM1DRD1LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778649-A4 | A PROCESS FOR PRODUCING PURE FORM OF 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO[2,3-b][1,5]BENZODIAZEPINE | JUBILANT ORGANOSYS LTD (IN) | 2008-09-10 | — | — | EP | disclosed |
| EP-1778649-A1 | A PROCESS FOR PRODUCING PURE FORM OF 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO[2,3-b][1,5]BENZODIAZEPINE | Jubilant Organosys Limited (IN) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006180-A1 | A PROCESS FOR PRODUCING PURE FORM OF 2-METHYL-4-(4-METHYL-1-PIPERAZINYL)-10H-THIENO[2,3-b][1,5]BENZODIAZEPINE | JUBILANT ORGANOSYS LIMITED (IN) | 2006-01-19 | — | — | WO | disclosed |