Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 8/20 | 1.00 |
| ▸ | GSK3B | P49841 | 8/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.68 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PRF1 | P14222 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143164 | 1.00 | GSK3A (1.00) | GSK3AGSK3BPIK3CGPIM1POLB | |
| SCHEMBL13587005 | 0.90 | GSK3A (0.81) | GSK3AGSK3BPIK3CGPIM1POLB | |
| SCHEMBL12990771 | 0.88 | GSK3A (0.79) | GSK3AGSK3BPIK3CGPIM1POLB | |
| SCHEMBL3365349 | 0.88 | GSK3A (0.79) | GSK3AGSK3BPIK3CGPIM1POLB | |
| SCHEMBL3365346 | 0.88 | GSK3A (0.79) | GSK3AGSK3BPIK3CGPIM1POLB | |
| SCHEMBL1065847 | 0.87 | GSK3A (0.77) | GSK3AGSK3BPIK3CGPOLBL3MBTL1 | |
| SCHEMBL1065845 | 0.87 | GSK3A (0.77) | GSK3AGSK3BPIK3CGPOLBL3MBTL1 | |
| SCHEMBL1064194 | 0.84 | GSK3A (0.74) | GSK3AGSK3BPIK3CGPOLBL3MBTL1 | |
| SCHEMBL1064195 | 0.84 | GSK3A (0.74) | GSK3AGSK3BPIK3CGPOLBL3MBTL1 | |
| SCHEMBL13388774 | 0.84 | GSK3A (0.72) | GSK3AGSK3BPIK3CGL3MBTL1PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294641-B2 | Heterocyclic compound for stimulating or inducing the growth of the hair or eyelashes and/or slowing down their loss, composition comprising it and its uses | L'OREAL (FR) | 2007-11-13 | — | — | US | disclosed |