SCHEMBL5143472

SCHEMBL5143472

CCN1C=CC(c2cc3cc4nc(cc5ccc(cc6nc(cc2[nH]3)C=C6)[nH]5)C=C4)=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5181959 0.85
SCHEMBL2439280 0.84 STAT3 (0.30)
SCHEMBL28449400 0.84
Hydrochloric Acid SCHEMBL4435884 0.83
Hydrochloric Acid SCHEMBL6515674 0.83
Iodide SCHEMBL9583490 0.83
SCHEMBL5143471 0.83 STAT3 (0.44)
Acetic Acid SCHEMBL9582014 0.79
Acetic Acid SCHEMBL9582356 0.79
Acetic Acid SCHEMBL9582773 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641391-A4 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE FRONTIER SCIENT INC (US) 2007-05-30 EP disclosed
EP-1641391-A2 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE Frontier Scientific, Inc. (US) 2006-04-05 EP disclosed
WO-2004110377-A2 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE FRONTIER SCIENTIFIC, INC. (US) 2004-12-23 WO disclosed