SCHEMBL5143471

SCHEMBL5143471

CCN1C=CC(c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)=CC1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.44
STAT1 P42224 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19718106 0.88 STAT3 (0.39) STAT3STAT1
SCHEMBL5181954 0.86 STAT3 (0.41) STAT3STAT1
SCHEMBL2439283 0.85 STAT3 (0.46) STAT3STAT1
SCHEMBL5900934 0.84 TERT (0.41)
SCHEMBL5143472 0.83
Hydrochloric Acid SCHEMBL8183377 0.82 TERT (0.40)
SCHEMBL30417810 0.82 TERT (0.40)
SCHEMBL8182072 0.82 STAT3 (0.44) STAT3STAT1
SCHEMBL25184071 0.81
Acetic Acid SCHEMBL9582779 0.80 STAT3 (0.44) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641391-A4 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE FRONTIER SCIENT INC (US) 2007-05-30 EP disclosed
EP-1641391-A2 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE Frontier Scientific, Inc. (US) 2006-04-05 EP disclosed
WO-2004110377-A2 PORPHYRINS AND METALLOPORPHYRINS FOR INHIBITING HEME IRON UPTAKE FRONTIER SCIENTIFIC, INC. (US) 2004-12-23 WO disclosed