SCHEMBL5144401

SCHEMBL5144401

NC(S)Cc1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.67
HTR2C P28335 1/20 0.67
HTR2B P41595 1/20 0.67
CYP1A2 P05177 1/20 0.50
CYP2A6 P11509 1/20 0.50
MC4R P32245 2/20 0.49
MC5R P33032 2/20 0.49
TACR1 P25103 2/20 0.48
MC3R P41968 1/20 0.46
MME P08473 2/20 0.43
ACE P12821 2/20 0.43
CPA1 P15085 2/20 0.43
ACE2 Q9BYF1 2/20 0.43
DPP4 P27487 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
SIGMAR1 Q99720 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17413319 0.80 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL11748582 0.80 HTR2A (0.67) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL31054190 0.80 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL31054149 0.80 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL268036 0.80 HTR2A (1.00) HTR2AHTR2CHTR2BCYP1A2CYP2A6
Hydrochloric Acid SCHEMBL5962875 0.78 HTR2A (0.96) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL3470527 0.78 HTR2A (0.65) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL5168955 0.78 HTR2A (0.65) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL1127612 0.77 HTR2A (0.53) HTR2AHTR2CHTR2BCYP1A2CYP2A6
SCHEMBL17407614 0.77 HTR2A (0.73) HTR2AHTR2CHTR2BCYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3027787-A2 ORGANIC DISULFIDE BASED CORROSION INHIBITORS Ecolab USA Inc. (US) 2016-06-08 EP claimed
EP-3027787-A2 ORGANIC DISULFIDE BASED CORROSION INHIBITORS Ecolab USA Inc. (US) 2016-06-08 EP disclosed
EP-1368509-A4 COMPOSITION AND METHOD FOR INHIBITION OF METAL CORROSION DONLAR CORP (US) 2007-08-01 EP disclosed
EP-1368509-A2 COMPOSITION AND METHOD FOR INHIBITION OF METAL CORROSION DONLAR CORPORATION (US) 2003-12-10 EP disclosed
WO-2000075399-A2 COMPOSITION AND METHOD FOR INHIBITION OF METAL CORROSION DONLAR CORPORATION (US) 2000-12-14 WO disclosed