Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC5R | P33032 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470527 | 1.00 | HTR2A (0.65) | HTR2AHTR2CHTR2BTACR1MC4R | |
| SCHEMBL9271615 | 0.84 | LTA4H (0.55) | HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL31307723 | 0.84 | LTA4H (0.55) | HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL29292157 | 0.83 | HTR2A (0.68) | HTR2AHTR2CHTR2BTACR1MC4R | |
| SCHEMBL3936172 | 0.83 | HTR2A (0.62) | HTR2AHTR2CHTR2BTACR1MC4R | |
| SCHEMBL1177623 | 0.83 | HTR2A (0.62) | HTR2AHTR2CHTR2BTACR1MC4R | |
| SCHEMBL3132304 | 0.83 | HTR2A (0.62) | HTR2AHTR2CHTR2BTACR1MC4R | |
| Hydrochloric Acid SCHEMBL6803543 | 0.83 | LTA4H (0.54) | HTR2AHTR2CHTR2BTACR1 | |
| SCHEMBL4666056 | 0.80 | HTR2A (0.64) | HTR2AHTR2CHTR2BTACR1MC4R | |
| SCHEMBL6024130 | 0.80 | HTR2A (0.64) | HTR2AHTR2CHTR2BTACR1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | PROCTER & GAMBLE (US) | 2018-11-01 | — | — | US | disclosed |
| EP-3365324-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | The Procter and Gamble Company (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
| US-7767388-B2 | Method for monitoring the stereoselectivity and relative rate of organic chemical reactions | NUTECH VENTURES (US) | 2010-08-03 | — | — | US | disclosed |
| US-7767388-B2 | Method for monitoring the stereoselectivity and relative rate of organic chemical reactions | NUTECH VENTURES (US) | 2010-08-03 | — | — | US | disclosed |
| EP-0999220-B1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC (US) | 2007-05-02 | — | — | EP | disclosed |
| US-7094869-B2 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH, INC. (US) | 2006-03-23 | — | — | US | disclosed |
| EP-0792289-B1 | LOW MOLECULAR WEIGHT PEPTIDOMIMETIC GROWTH HORMONE SECRETAGOGUES | GENENTECH INC (US) | 2000-07-12 | — | — | EP | disclosed |
| US-6034216-A | Low molecular weight peptidomimetic growth hormone secretagogues | GENENTECH INC. (US) | 2000-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | SRM, ACMSD, CUTA | HTR2A 49/4885HTR2C 108/4885HTR2B 89/4885 |
| US-20060063807-A1 | Low molecular weight peptidomimetic growth hormone secretagogues | GHSR, GHRHR, IGFBP1 | HTR2A 499/4885HTR2C 1298/4885HTR2B 1183/4885 |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, ACMSD, SRM | HTR2A 50/4885HTR2C 99/4885HTR2B 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.