⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537058 | 0.59 | — | — | |
| SCHEMBL208115 | 0.57 | — | — | |
| SCHEMBL22471674 | 0.51 | — | — | |
| SCHEMBL12179431 | 0.50 | — | — | |
| SCHEMBL10566076 | 0.49 | — | — | |
| SCHEMBL1004526 | 0.46 | — | — | |
| SCHEMBL2398119 | 0.46 | — | — | |
| SCHEMBL10793630 | 0.42 | — | — | |
| SCHEMBL43805 | 0.33 | — | — | |
| SCHEMBL452580 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| CN-110740996-B | Covalent small molecule DCN1 inhibitors and methods of treatment using the same | 密执安大学评议会 | 2024-01-09 | — | — | CN | disclosed |
| EP-3609876-B1 | COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2022-03-30 | — | — | EP | disclosed |
| US-20200109167-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV MICHIGAN REGENTS (US) | 2020-04-09 | — | — | US | disclosed |
| EP-3609876-A1 | COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3601245-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018191199-A1 | COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-10-18 | — | — | WO | disclosed |
| US-20180289677-A1 | Covalent Small Molecule DCN1 Inhibitors and Therapeutic Methods Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-10-11 | — | — | US | disclosed |
| WO-2018183411-A1 | SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-10-04 | — | — | WO | disclosed |
| US-7166422-B2 | Silver halide color photographic material, and method of image formation | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-6649336-B2 | Having silver chloroiodide or silver chloroiodobromide grains of high silver chloride content, doped with a hexacyano complex, and containing a methine dye of given formula; reduced fogging | FUJI PHOTO FILM CO., LTD (JP) | 2003-11-18 | — | — | US | disclosed |
| US-6566044-B2 | High speed photography; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 2003-05-20 | — | — | US | disclosed |
| US-20030087210-A1 | Silver halide color photographic material, and method of image formation | FUJI PHOTO FILM CO., LTD. | 2003-05-08 | — | — | US | disclosed |
| US-20020110764-A1 | Silver halide photographic material | FUJIFILM CORPORATION (JP) | 2002-08-15 | — | — | US | disclosed |
| US-20020072019-A1 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2002-06-13 | — | — | US | disclosed |
| EP-1139164-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 2001-10-04 | — | — | EP | disclosed |