Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27816299 | 1.00 | LMNA (0.64) | LMNAEGLN1ALKBH5SUCNR1KMT2A | |
| Beta-Alanine SCHEMBL21500 | 0.96 | — | — | |
| Beta-Alanine SCHEMBL18281080 | 0.96 | — | — | |
| Beta-Alanine SCHEMBL20411566 | 0.96 | — | — | |
| Beta-Alanine SCHEMBL29449904 | 0.96 | — | — | |
| Beta-Alanine SCHEMBL18281085 | 0.96 | — | — | |
| Beta-Alanine SCHEMBL23190 | 0.96 | LMNA (0.65) | LMNAEGLN1ALKBH5SUCNR1KMT2A | |
| Beta-Alanine SCHEMBL65469 | 0.93 | — | — | |
| Beta-Alanine SCHEMBL20516078 | 0.93 | — | — | |
| Beta-Alanine SCHEMBL11787358 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166422-B2 | Silver halide color photographic material, and method of image formation | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| CN-1266540-C | Silver halide color photographic material and image forming method | FUJI PHOTO FILM CO LTD (JP) | 2006-07-26 | — | — | CN | disclosed |
| CN-1506754-A | Concentrated bleaching-fixing agent composition for silver halide colour photographic material | 柯尼卡美能达控股株式会社 | 2004-06-23 | — | — | CN | disclosed |
| US-20030087210-A1 | Silver halide color photographic material, and method of image formation | FUJI PHOTO FILM CO., LTD. | 2003-05-08 | — | — | US | disclosed |
| CN-1387086-A | Silver halide color photographic material and image forming method | FUJI PHOTO FILM CO LTD (JP) | 2002-12-25 | — | — | CN | disclosed |
| US-6479229-B2 | MULTILAYER; CONTAINING P-PHENYLENEDIAMINE DEVELOPER | FUJI PHOTO FILM CO. LTD. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-20020009679-A1 | Silver halide color photographic material and development processing method of the same | FUJI PHOTO FILM CO., LTD. | 2002-01-24 | — | — | US | disclosed |
| US-6284446-B1 | MULTILAYER PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| US-6043007-A | Color developer composition for photography | FUJI PHOTO FILM CO., LTD. (JP) | 2000-03-28 | — | — | US | disclosed |