Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.71 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095760 | 0.88 | MAOB (0.72) | MEN1KMT2ACTDSP1SLC16A3MAOB | |
| SCHEMBL11225033 | 0.88 | SLC16A3 (0.72) | MEN1KMT2ACTDSP1SLC16A3MAOB | |
| SCHEMBL6836135 | 0.83 | SLC16A3 (0.66) | MEN1KMT2ACTDSP1SLC16A3MAOB | |
| SCHEMBL5467109 | 0.83 | MEN1 (0.69) | MEN1KMT2ACTDSP1SLC16A3MAOB | |
| SCHEMBL51506 | 0.83 | MAOB (0.76) | MEN1KMT2ASLC16A3MAOBHPGD | |
| SCHEMBL2030497 | 0.83 | SLC16A3 (0.81) | MEN1KMT2ASLC16A3MAOBCA12 | |
| SCHEMBL2031125 | 0.82 | MEN1 (0.71) | MEN1KMT2ACTDSP1SLC16A3MAOB | |
| SCHEMBL27459448 | 0.81 | MAOB (0.77) | MEN1KMT2ASLC16A3MAOBHPGD | |
| SCHEMBL2035874 | 0.81 | MEN1 (0.72) | MEN1KMT2ASLC16A3MAOBCA12 | |
| SCHEMBL2032560 | 0.81 | MEN1 (0.73) | MEN1KMT2ACTDSP1MAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624900-A4 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | UNIV CALIFORNIA (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-03-08 | — | — | US | disclosed |
| EP-1624900-A2 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2005040337-A2 | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070053831-A1 | Methods for binding agents to b-amyloid plaques | APBA1, CLTB, FABP7 | MEN1 2220/4885KMT2A 4548/4885CTDSP1 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.