SCHEMBL2035874

SCHEMBL2035874

COc1ccc(C(=O)c2cc3ccc(N(C)C)cc3oc2=O)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.72
KMT2A Q03164 4/20 0.72
PKM P14618 2/20 0.72
ALDH1A1 P00352 6/20 0.67
KDM4E B2RXH2 4/20 0.67
RAB9A P51151 2/20 0.67
NPC1 O15118 1/20 0.67
POLB P06746 1/20 0.67
SLC16A3 O15427 2/20 0.63
MAOB P27338 6/20 0.60
GAA P10253 3/20 0.56
HPGD P15428 3/20 0.56
GLA P06280 2/20 0.56
HSD17B10 Q99714 1/20 0.56
LMNA P02545 2/20 0.56
MAOA P21397 2/20 0.55
HSD11B1 P28845 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
CYP2C19 P33261 2/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11225033 0.90 SLC16A3 (0.72) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL2034492 0.87 ALDH1A1 (0.85) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL2028924 0.87 MAOB (0.76) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL6836135 0.85 SLC16A3 (0.66) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL5467109 0.85 MEN1 (0.69) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL51506 0.85 MAOB (0.76) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL2030497 0.85 SLC16A3 (0.81) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL28015513 0.84 MEN1 (1.00) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL27459448 0.83 MAOB (0.77) MEN1KMT2APKMALDH1A1KDM4E
SCHEMBL15662702 0.81 ALDH1A1 (0.79) MEN1KMT2APKMALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4736835-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-12527725-B2 Solvent-free dental adhesive composition KURARAY NORITAKE DENTAL INC. (JP) 2026-01-20 US disclosed
EP-4649938-A1 DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-11-19 EP disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
EP-4578439-A1 DENTAL ADHESIVE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2025-07-02 EP disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-03-04 US disclosed
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-25 US disclosed
US-20100036075-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION KURARAY MEDICAL INC. (JP) 2010-02-11 US disclosed
EP-2133368-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-12-16 EP disclosed
EP-2112178-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2112177-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION Kuraray Medical Inc. (JP) 2009-10-28 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2070935-A1 NOVEL COMPOUND, COMPOSITION COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF POLYMERIZABLE AMIDE Kuraray Medical Inc. (JP) 2009-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048761-A1 POLYMERIZABLE MONOMER-CONTAINING COMPOSITION WDR82, PWWP2B, WDR5 MEN1 2863/4885KMT2A 2288/4885PKM 3346/4885
US-20250213433-A1 SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE CDH1, MACF1, ICAM1 MEN1 4464/4885KMT2A 3947/4885PKM 4818/4885
US-12527725-B2 Solvent-free dental adhesive composition CDH1, ITGA1, ITGB8 MEN1 2429/4885KMT2A 2358/4885PKM 4374/4885
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A MEN1 4009/4885KMT2A 2189/4885PKM 1699/4885
US-20100048762-A1 COMPOSITION AND DENTAL MATERIAL PHOSPHO1, PDS5B, ITGB5 MEN1 4053/4885KMT2A 1690/4885PKM 4152/4885
US-20100056665-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL ITGA1, COL1A1, MACF1 MEN1 1533/4885KMT2A 1150/4885PKM 1851/4885
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A MEN1 2119/4885KMT2A 1041/4885PKM 3777/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL MEN1 1873/4885KMT2A 2306/4885PKM 3656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.